Williams is 2-5 in her last seven Grand Slam finals since going 8-0 in her previous eight. Since winning the 2017 Australian Open, Williams has advanced to the finals at Wimbledon and the US Open in 2018 and Wimbledon in 2019, but has fallen short in each of those matchups. The six-time US Open champion is going off as a +350 favorite to win the tournament at sportsbooks monitored by. Williams hopes to earn the 24th Grand Slam title of her career with a win at the 2019 US Open. Serena Williams has won the US Open six times in her career including a run of three wins in a row from 2012 through 2014.